Toader, Alice-MariaCampbell, Marion KQuint, Jennifer KRobling, MichaelSydes, Matthew RThorn, JoannaWright-Hughes, AlexandraYu, Ly-MeeAbbott, Tom E FBond, SimonCaskey, Fergus JClout, MadeleineCollinson, MichelleCopsey, BethanDavies, GwynethDriscoll, TimothyGamble, CarrolGriffin, Xavier LHamborg, ThomasHarris, JessicaHarrison, David AHarji, DeenaHenderson, Emily JLogan, PipLove, Sharon BMagee, Laura AO'Brien, AlastairPufulete, MariaRamnarayan, PadmanabhanSaratzis, AthanasiosSmith, JoSolis-Trapala, IvonneStubbs, CliveFarrin, AmandaWilliamson, Paula2024-11-282024-11-282024-01-29Toader, A-M, Campbell, M K, Quint, J K, Robling, M, Sydes, M R, Thorn, J, Wright-Hughes, A, Yu, L-M, Abbott, T E F, Bond, S, Caskey, F J, Clout, M, Collinson, M, Copsey, B, Davies, G, Driscoll, T, Gamble, C, Griffin, X L, Hamborg, T, Harris, J, Harrison, D A, Harji, D, Henderson, E J, Logan, P, Love, S B, Magee, L A, O'Brien, A, Pufulete, M, Ramnarayan, P, Saratzis, A, Smith, J, Solis-Trapala, I, Stubbs, C, Farrin, A & Williamson, P 2024, 'Using healthcare systems data for outcomes in clinical trials : issues to consider at the design stage', Trials, vol. 25, no. 1, 94. https://doi.org/10.1186/s13063-024-07926-z1745-6215PubMedCentral: PMC10823676https://hdl.handle.net/2164/24676Acknowledgements We are grateful to those completing the consultation. Fiona Lugg-Widger was a co-applicant for the PRIMORANT study, leading for the second prioritised project and led the COMORANT study that identified research priorities in using routine data.91246156engHealthcare systems dataOutcomesClinical trialsRoutinely collected dataData validityRegistriesR MedicineSupplementary InformationRJournal article10.1186/s13063-024-07926-z251