Petela, Naomi J.Gligoris, Thomas G.Metson, JeanLee, Byung-GilVoulgaris, MenelaosHu, BinKikuchi, SotaroChapard, ChristopheChen, WentaoRajendra, EesonSrinivisan, MadhusudhanYu, HongtaoLöwe, JanNasmyth, Kim A.2020-04-132020-04-132018-06-21Petela, N J, Gligoris, T G, Metson, J, Lee, B-G, Voulgaris, M, Hu, B, Kikuchi, S, Chapard, C, Chen, W, Rajendra, E, Srinivisan, M, Yu, H, Löwe, J & Nasmyth, K A 2018, 'Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5', Molecular Cell, vol. 70, no. 6, pp. 1134-1148.e7. https://doi.org/10.1016/j.molcel.2018.05.0221097-2765ORCID: /0000-0001-6316-2830/work/50934077https://hdl.handle.net/2164/14051Acknowledgements We are grateful to Adele Marston for sharing yeast strains; Peter West for programming support; and Tatiana Wilson, Isobel Johns, and Stefanos Skylakakis for invaluable technical assistance. We thank all members of the Nasmyth group for valuable discussions. This work was funded by Cancer Research UK (C573/A12386 to K.A.N.), the Wellcome Trust (107935/Z/15/Z to K.A.N., 202062/Z/16/Z to B.H., and 202754/Z/16/Z to J.L.), the Medical Research Council (MR/L018047/1 to K.A.N. and U105184326 to J.L.), the European Research Council (294401 to K.A.N.), and the Welch Foundation (I-1441 to H.Y.). H.Y. is an Investigator with the Howard Hughes Medical Institute.237274108engSDG 3 - Good Health and Well-beingcohesinScc2Pds5Scc1cohesionATPaseloadingHAWKsR Medicine (General)Cancer Research UKC573/A12386Wellcome Trust107935/Z/15/Z202062/Z/16/Z202754/Z/16/ZMedical Research Council (MRC)MR/L018047/1U105184326European Research Council294401OtherI-1441Welch FoundationSupplementary DataR1Journal article10.1016/j.molcel.2018.05.022http://europepmc.org/abstract/med/29932904706