Cardoso Borges, Fábiovan der Graaf, Winette T ASaesen, RobbeAebi, StefanAmariutei, Ana EBekelman, JustinGorlia, ThierryHulstaert, FrankHuys, IsabelleKluetz, PaulMorris, Michael JPatil, VijayPrindiville, Sheila ASchilsky, Richard LThomson, AndrewTreweek, ShaunWeller, MichaelZuidgeest, MiraRetel, ValescaLacombe, Denis2025-05-122025-05-122025-05-01Cardoso Borges, F, van der Graaf, W T A, Saesen, R, Aebi, S, Amariutei, A E, Bekelman, J, Gorlia, T, Hulstaert, F, Huys, I, Kluetz, P, Morris, M J, Patil, V, Prindiville, S A, Schilsky, R L, Thomson, A, Treweek, S, Weller, M, Zuidgeest, M, Retel, V & Lacombe, D 2025, 'Defining the role of pragmatic clinical trials in cancer clinical research : outcomes of a collaborative workshop hosted by the European Organisation for Research and Treatment of Cancer', The Lancet Oncology, vol. 26, no. 5, pp. e253-e263. https://doi.org/10.1016/S1470-2045(24)00756-31470-2045RIS: urn:2E391DEFF0DF82F5EC37514140C6E729ORCID: /0000-0002-7239-7241/work/186968373https://hdl.handle.net/2164/25428We acknowledge and thank all the speakers, panellists, and participants for their interest and enthusiasm in this workshop on pragmatic clinical trials organised by the EORTC. We also thank the EORTC staff for their dedication, and the stakeholder groups and interested organisations involved, especially the European Medicines Agency, and particularly Francesco Pignatti and Caroline Voltz, for their support and advice. During the preparation of this work the authors used ChatGPT v4.0 in order to refine the readability and language of the work. After using ChatGPT v4.0, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication.10409843engSDG 3 - Good Health and Well-beingRC0254 Neoplasms. Tumors. Oncology (including Cancer)RC0254Defining the role of pragmatic clinical trials in cancer clinical research : outcomes of a collaborative workshop hosted by the European Organisation for Research and Treatment of CancerJournal article10.1016/S1470-2045(24)00756-3https://www.sciencedirect.com/science/article/pii/S1470204524007563265