Yamaguchi, TakuyaChang, Chia JungKarger, AxelKeller, MarkusPfaff, FlorianWangkahart, EakapolWang, TiehuiSecombes, Christopher J.Kimoto, AzusaFurihata, MitsuruHashimoto, KeiichiroFischer, UweDijkstra, Johannes M.2021-05-052021-05-052020-10-29Yamaguchi, T, Chang, C J, Karger, A, Keller, M, Pfaff, F, Wangkahart, E, Wang, T, Secombes, C J, Kimoto, A, Furihata, M, Hashimoto, K, Fischer, U & Dijkstra, J M 2020, 'Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response', Frontiers in Immunology, vol. 11, 549319. https://doi.org/10.3389/fimmu.2020.5493191664-3224https://hdl.handle.net/2164/16387Acknowledgments We thank Mrs. Susann Schares and Katrin Giesow for excellent technical assistance and Dr. Gunther Keil for his valuable advice regarding expression of recombinant proteins in insect cells. We also thank Prof. Oriol Sunyer from the University of Pennsylvania, USA, for providing us mAbs against rainbow trout CD4. A large part of this manuscript has been released as a pre-print (116). Funding TY and UF were supported by the EU FP7 Grant 311993 (TARGETFISH) and the German Research Council Grant No. FI 604/7-1. JD was supported by the Ministry of Education, Culture, Sports, Science and Technology, Japan, Grants-in-Aid for Scientific Research No. 25450319. TW received funding from the MASTS pooling initiative (The Marine Alliance for Science and Technology for Scotland), that was funded by the Scottish Funding Council (grant reference HR09011). EW was supported by the Ministry of Science and Technology of Thailand and Mahasarakham University.306748312engevolutionfishIL-15IL-15-likeIL-15RαIL-2type 2 immunityQH301 BiologyImmunology and AllergyImmunologyEuropean CommissionEU FP7 Grant 311993Scottish Funding CouncilHR09011Supplementary DataQH301Journal article10.3389/fimmu.2020.549319http://www.scopus.com/inward/record.url?scp=85096022299&partnerID=8YFLogxKhttps://www.frontiersin.org/articles/10.3389/fimmu.2020.549319/full#supplementary-material11