Pradhan, ArnabAvelar, Gabriela M.Bain, Judith M.Childers, DelmaPelletier, ChloeLarcombe, Daniel E.Shekhova, ElenaNetea, Mihai G.Brown, Gordon D.Erwig, LarsGow, Neil A. R.Brown, Alistair J. P.2019-12-242019-12-242019-11-22Pradhan, A, Avelar, G M, Bain, J M, Childers, D, Pelletier, C, Larcombe, D E, Shekhova, E, Netea, M G, Brown, G D, Erwig, L, Gow, N A R & Brown, A J P 2019, 'Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion', Nature Communications, vol. 10, 5315. https://doi.org/10.1038/s41467-019-13298-92041-1723ORCID: /0000-0003-2869-7332/work/76975994ORCID: /0000-0002-1060-0419/work/112075827https://hdl.handle.net/2164/13428Data Availability The authors declare that the data supporting the findings of this study are available within the paper (and its supplementary information files). Acknowledgements We are grateful to Raif Yuecel, Linda Duncan, Kimberley Sim and Ailsa Laird in the Iain Fraser Cytometry Centre, and to Kevin MacKenzie, Debbie Wilkinson, Gillian Milne and Lucy Wight in our Microscopy and Histology Core Facility for their superb support. We thank Katja Schafer and Angela Lopez for help with the design of primers and for providing CRISPR-Cas9 protocols for mutant construction. We also thank our colleagues in the Candida community, and in particular Jan Quinn, Guanghua Huang, Suzanne Noble, Karl Kuchler, Patrick van Dijck, Rich Calderone and Malcolm Whiteway for providing strains used in this study. This work was funded by a programme grant from the UK Medical Research Council [www.mrc.ac.uk: MR/M026663/1], and by PhD studentships from the University of Aberdeen to AP, DL. The work was also supported by the Medical Research Council Centre for Medical Mycology and the University of Aberdeen [MR/N006364/1], by the European Commission [FunHoMic: H2020-MSCA-ITN-2018-812969], and by the Wellcome Trust via Investigator, Collaborative, Equipment, Strategic and Biomedical Resource awards [www.wellcome.ac.uk: 075470, 086827, 093378, 097377, 099197, 101873, 102705, 200208]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.142399077engCandida albicansimmune evasioncell wallpathogen associated molecular patternsβ-glucaniron responsesFtr1Sef1cAMP-protein kinase A signallingR Medicine (General)Medical Research Council (MRC)MR/M026663/1MR/N006364/1European CommissionH2020-MSCA-ITN-2018-812969Wellcome Trust075470086827093378097377099197101873102705200208Supplementary DataR1Journal article10.1038/s41467-019-13298-910