Ubah, Obinna C.Steven, JohnKovaleva, MarinaFerguson, LauraBarelle, CharlottePorter, Andrew J. R.Barelle, Caroline J.2018-01-032018-01-032017-12-22Ubah, O C, Steven, J, Kovaleva, M, Ferguson, L, Barelle, C, Porter, A J R & Barelle, C J 2017, 'Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralising Potency and Multifunctionality, Generated for Therapeutic Development', Frontiers in Immunology, vol. 8, 1780. https://doi.org/10.3389/fimmu.2017.017801664-3224http://hdl.handle.net/2164/9849ACKNOWLEDGMENTS The authors wish to acknowledge the funding support for this work from MSD/Scottish Universities Life Sciences Alliance (SULSA), Scottish Enterprise, the Biotechnology and Biological Sciences Research Council (BBSRC), and the University of Aberdeen. FUNDING Grateful for support from Biotechnology and Biological Sciences Research Council (BB/K010905/1), Scottish Enterprise [VNAR_001 (2012)], Scottish Universities Life Sciences Alliance/ MSD (MSD01_A_Porter-Teismann), and the College of Life Sciences and Medicine, University of Aberdeen (Fee bursary to OU).131344258engvNARTNF-αphage displaycytokine neutralisationchronic inflammationshark IgNARbiparatopic/bispecific binding domainanti-TNF biologicsshark immunisationsingle binding domainvariable new antigen receptortumor necrosis factor-αbinding domainQR180 ImmunologyBiotechnology and Biological Sciences Research Council (BBSRC)BB/K010905/1QR180Journal article10.3389/fimmu.2017.017808