Cao, HuanAntonopoulos, AristotelisHenderson, SadieWassall, Heather J.hBrewin, JohnMasson, AlannaShepherd, JennaKonieczny, GabrielaPatel, BhinalWilliams, Maria-LouiseDavie, AdamForrester, Megan AmyHall, Lindsay SusanMinter, BeverleyTampakis, DimitrisMoss, MichaelLennon, CharlottePickford, WendyErwig, LarsRobertson, BeverleyDell, AnneBrown, GordonWilson, HeatherRees, David C.Haslam, Stuart MRowe, J. AlexandraBarker, RobertVickers, Mark2021-03-312021-03-312021-03-19Cao, H, Antonopoulos, A, Henderson, S, Wassall, H J H, Brewin, J, Masson, A, Shepherd, J, Konieczny, G, Patel, B, Williams, M-L, Davie, A, Forrester, M A, Hall, L S, Minter, B, Tampakis, D, Moss, M, Lennon, C, Pickford, W, Erwig, L, Robertson, B, Dell, A, Brown, G, Wilson, H, Rees, D C, Haslam, S M, Rowe, J A, Barker, R & Vickers, M 2021, 'Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance', Nature Communications, vol. 12, no. 1, 1792. https://doi.org/10.1038/s41467-021-21814-z2041-1723ORCID: /0000-0002-1407-7274/work/91891237ORCID: /0000-0002-3154-1040/work/91891820https://hdl.handle.net/2164/16159Acknowledgements We are grateful for the assistance provided by both the Microscopy and Histology Core Facility, and the Iain Fraser Cytometry Centre, at the University of Aberdeen. We thank Ann Wheeler and Matt Pearson from Edinburgh Super-Resolution Imaging Consortium for technical support with 3D SIM microscopy. We also thank Janet A. Willment and Bernard Kerscher, supervised by G.D.B., for providing the Fc fusion proteins, Jeanette A. Wagener, supervised by Neil A.R.G. Gow, for providing high purity chitin, Jan Westland for obtaining blood samples and Paul Crocker for useful discussions. Principal funding for this project was provided by Wellcome Trust grant 094847 (R.N.B., L.P.E., M.A.V.). In addition, support was provided by Biotechnology and Biological Sciences Research Council grants BBF0083091 (A.D. and S.M.H.) and BBK0161641 (A.D. and S.M.H.), Wellcome Trust grant 082098 (A.D.), Wellcome Trust grants 97377, 102705 (G.D.B.), and funding for the MRC Centre for Medical Mycology at the University of Aberdeen MR/N006364/1 (G.D.B.).133277453engSDG 3 - Good Health and Well-beingGlycobiologyMalariaPattern recognition receptorssickle cell diseaseR MedicineWellcome Trust09484708209897377102705Biotechnology and Biological Sciences Research Council (BBSRC)BBF0083091Medical Research Council (MRC)MR/N006364/1Supplementary DataRJournal article10.1038/s41467-021-21814-zhttp://www.scopus.com/inward/record.url?scp=85102890135&partnerID=8YFLogxK121