Schelter, Bjoern O.Shiells, HelenBaddeley, Thomas C.Rubino, Christopher M.Ganesan, HarishHammel, JeffreyVuksanovic, VesnaStaff, Roger T.Murray, Alison D.Bracoud, LucRiedel, GernotGauthier, SergeJia, JianpingBentham, PeterKook, KarinStorey, John M. D.Harrington, Charles R.Wischik, Claude M.2019-12-022019-12-022019-11-26Schelter, B O, Shiells, H, Baddeley, T C, Rubino, C M, Ganesan, H, Hammel, J, Vuksanovic, V, Staff, R T, Murray, A D, Bracoud, L, Riedel, G, Gauthier, S, Jia, J, Bentham, P, Kook, K, Storey, J M D, Harrington, C R & Wischik, C M 2019, 'Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease', Journal of Alzheimer's Disease, vol. 72, no. 3, pp. 931-946. https://doi.org/10.3233/JAD-1907721387-2877ORCID: /0000-0002-5261-5467/work/73579158ORCID: /0000-0003-4915-4847/work/76976621ORCID: /0000-0003-2250-3920/work/173415902https://hdl.handle.net/2164/13339ACKNOWLEDGMENTS We gratefully acknowledge study investigators and the generosity of study participants. We gratefully acknowledge Professor Gordon Wilcock for critical review and commentary on drafts of the manuscript. Author’s disclosures available online (https://www.j-alz.com/manuscript-disclosures/19-0772r1). SUPPLEMENTARY MATERIAL The supplementary material is available in the electronic version of this article: http://dx.doi.org/10.3233/JAD-190772. Availability of data and materials The datasets and analyses used during the current study are available from the corresponding author on reasonable request.16762527engAcetylcholinesterase inhibitorAlzheimer’s diseaseclinical trialsdrug interactionleucomethylthioniniumpopulation pharmacokineticshydromethylthionineR Medicine (General)Supplementary DataR1Journal article10.3233/JAD-190772723