Hedin, Charlotte RMcCarthy, Neil ELouis, PetraFarquharson, FredaMcCartney, SaraStagg, Andrew JLindsay, James OWhelan, Kevin2022-06-222022-06-222021-08Hedin, C R, McCarthy, N E, Louis, P, Farquharson, F, McCartney, S, Stagg, A J, Lindsay, J O & Whelan, K 2021, 'Prebiotic fructans have greater impact on luminal microbiology and CD3+ T cells in healthy siblings than patients with Crohn’s disease : a pilot study investigating the potential for primary prevention of inflammatory bowel disease', Clinical Nutrition, vol. 40, no. 8, pp. 5009-5019. https://doi.org/10.1016/j.clnu.2021.05.0330261-5614ORCID: /0000-0003-2115-2399/work/101749490https://hdl.handle.net/2164/18739Funding This work was supported by a clinical research fellowship granted by the charity Core (Guts UK) (CRH). FMF and PL received financial support from the Scottish Government Rural and Environment Science and Analytical Services. Acknowledgments The authors would like to acknowledge BENEO-Orafti, Teinen, Belgium who provided the oligofructose-enriched inulin. The authors would like to thank the patients and the siblings who generously participated in this study.11504529engSDG 3 - Good Health and Well-beingPrebioticsCrohn’s diseasemicrobiotaPre-diseasefirst-degree relativepreventionR MedicineRA0421 Public health. Hygiene. Preventive MedicineNutrition and DieteticsCritical Care and Intensive Care MedicineRural and Environmental Science and Analytical Services (RESAS)Supplementary DataRRA0421Journal article10.1016/j.clnu.2021.05.033http://www.scopus.com/inward/record.url?scp=85111883698&partnerID=8YFLogxK408