Avgustinova, AlexandraIravani, MarjanRobertson, DavidFearns, AntonyGao, QiongKlingbeil, PamelaHanby, Andrew MSpeirs, ValerieSahai, ErikCalvo, FernandoIsacke, Clare M2018-07-202018-07-202016-01-18Avgustinova, A, Iravani, M, Robertson, D, Fearns, A, Gao, Q, Klingbeil, P, Hanby, A M, Speirs, V, Sahai, E, Calvo, F & Isacke, C M 2016, 'Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness', Nature Communications, vol. 7, 10305. https://doi.org/10.1038/ncomms103052041-1723PubMedCentral: PMC4735631ORCID: /0000-0002-0602-4666/work/72631293http://hdl.handle.net/2164/10774This work was funded by Breakthrough Breast Cancer (recently merged with Breast Cancer Campaign forming Breast Cancer Now; C.M.I.), Cancer Research UK (A.A., E.S. and CMI) and Breast Cancer Campaign (V.S. and A.H.). F.C. is currently funded by The Institute of Cancer Research and Worldwide Cancer Research. We acknowledge NHS funding to the NIHR Biomedical Research Centre at The Royal Marsden and the ICR. We thank the Breakthrough Histopathology Facility, Cambridge Genomic Services for the gene expression analysis, Balazs Gyorffy for providing the clinical breast cancer outcome data, Antoinette van Weverwijk for help with the in vivo assays, Fredrik Wallberg for help with the FACSorting, Andrea Morandi for help with the TMA analysis, Patricia Salinas for the Wnt7a cDNA construct and helpful discussions and Lorenzo Melchor for the pDEST/pHIV-H2BmRFP-rfa_verB Gateway cloning vector.144000601engSDG 3 - Good Health and Well-beingAnimalsBreast NeoplasmsFemaleFibroblastsGene Expression Regulation, NeoplasticHumansMiceMice, Inbred BALB CNIH 3T3 CellsWnt ProteinsJournal ArticleResearch Support, Non-U.S. Gov'tR MedicineSupplementary DataRJournal article10.1038/ncomms103057