Hyötyläinen, TuuliaMcGlinchey, AidanSalihovic, SamiraSchubert, AntoniaDouglas, AlexHay, David CO'Shaughnessy, Peter JIredale, John PShaw, SophieFowler, Paul AOrešič, Matej2024-01-092024-01-092024-01Hyötyläinen, T, McGlinchey, A, Salihovic, S, Schubert, A, Douglas, A, Hay, D C, O'Shaughnessy, P J, Iredale, J P, Shaw, S, Fowler, P A & Orešič, M 2024, 'In utero exposures to perfluoroalkyl substances and the human fetal liver metabolome in Scotland : a cross-sectional study', The Lancet Planetary Health, vol. 8, no. 1, pp. e5-e17. https://doi.org/10.1016/S2542-5196(23)00257-72542-5196RIS: urn:8DE822DA696DBD30B7F28E802437FA1FORCID: /0000-0001-6606-1058/work/150761646ORCID: /0000-0002-4831-9075/work/150762033https://hdl.handle.net/2164/22516The Fetal Human study was funded by the UK Medical Research Council (MR/L010011/1) to PAF, PJO’S, JPI, DCH, and AD, by the Seventh Framework Programme of the European Union under Grant Agreement 212885, and by NHS Grampian Endowments grants (08/02, 09/12, 13/56, and 15/1/010) to PAF. The metabolomics and exposomics study was supported by the Swedish Research Council (to TH and MO; grants 2016-05176 and 2020-03674), Formas (to TH and MO; grant 2019-00869), Novo Nordisk Foundation (to TH; grant NNF20OC0063971), Research Council of Finland (to MO; grant 333981), the Inflammation in human early life: targeting impacts on life-course health consortium funded by the Horizon Europe Program of the European Union (Grant Agreement 101094099 to MO, TH, and PAF), and the framework of the European Partnership for the Assessment of Risks from Chemicals, and has received funding from the European Union's Horizon Europe research and innovation programme (grant agreement 101057014). Views and opinions expressed are, however, those of the author(s) only and do not necessarily reflect those of the European Union or the Health and Digital Executive Agency. Neither the European Union nor the granting authority can be held responsible for them. The authors would like to thank (1) the Fowler team members, NHS Grampian research nurses, and staff at the Pregnancy Counselling Service for their essential work in recruiting, collecting, and processing fetuses; and (2) the Centre for Genome Enabled Biology and Medicine, University of Aberdeen, for carrying out the RNA-Seq. The RNA-Seq data analysis was supported by use of the University of Aberdeen Maxwell High Performance Computer Cluster.136177895engSubstantive connection via an eligible employment contractSDG 3 - Good Health and Well-beingGE Environmental SciencesMedical Research Council (MRC)MR/L010011/1European Research Council212885101094099GEJournal article10.1016/S2542-5196(23)00257-781