McIlroy, GeorgeSuchacki, KarlaRoelofs, Anke JYang, WulinFu, YanyunBai, BoWallace, Robert Jde Bari, CosimoCawthorn, William PHan, WeipingDelibegovic, MirelaRochford, Justin J.2018-05-022018-05-022018-04-01McIlroy, G, Suchacki, K, Roelofs, A J, Yang, W, Fu, Y, Bai, B, Wallace, R J, de Bari, C, Cawthorn, W P, Han, W, Delibegovic, M & Rochford, J J 2018, 'Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease', Molecular Metabolism, vol. 10, pp. 55-65. https://doi.org/10.1016/j.molmet.2018.01.0192212-8778ORCID: /0000-0002-5020-4939/work/53729080ORCID: /0000-0003-4230-4355/work/102133117ORCID: /0000-0001-6193-3152/work/160847580http://hdl.handle.net/2164/10405Acknowledgements: The authors would like to thank Dr Cristian Olarte-Sanchez for his help with metabolic studies, James Redmore and James Thorburn for their contributions to data collection and analysis, Alison Richmond, Susan Clark and Ausra Lionikiene for technical support, and staff at the University of Aberdeen's Medical Research Facility and Microscopy & Histology Facility. We are very grateful for the gift of the Adiponectin-Cre mice from Dr. Evan Rosen (Beth Israel Deaconess Medical Centre and Harvard Medical School, Boston, USA). Work was supported by the Medical Research Council (GDM/JJR; MR/L002620/1, MC/PC/15077, KS/WPC; MR/M021394/1, AJR/CDB; MR/L022893/1), the Biotechnology and Biological Sciences Research Council (JJR; BB/K017772/1), the British Heart Foundation (MD; PG/14/43/30889, KS/WPC; BHF CoRE Bioinformatics Grant), NHS Grampian Endowments (AJR/CDB/JJR; Grant No. 16/11/032) and the NHS Grampian Rheumatology Department.111949543engBSCL2seipinCGL2lipodystrophyadipose tissueBrowningR MedicineMedical Research Council (MRC)MR/L002620/1MC/PC/15077,MR/M021394/1MR/L022893/1Biotechnology and Biological Sciences Research Council (BBSRC)BB/K017772/1British Heart FoundationPG/14/43/30889Supplementary DataRJournal article10.1016/j.molmet.2018.01.01910