Arastoo, MohammadPenny, Lewis KirkLofthouse, Richard AndrewAbdallah, AyaAbrahamsson, AnnaMarini, PietroMelis, ValeriaRiedel, GernotHarrington, CharlesWischik, ClaudePorter, AndrewPalliyil, Soumya2024-10-212024-10-212024-10-02Arastoo, M, Penny, L K, Lofthouse, R A, Abdallah, A, Abrahamsson, A, Marini, P, Melis, V, Riedel, G, Harrington, C, Wischik, C, Porter, A & Palliyil, S 2024, 'High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease', Alzheimer's Research & Therapy, vol. 16, 209. https://doi.org/10.1186/s13195-024-01561-11758-9193ORCID: /0000-0002-0805-4949/work/170011412ORCID: /0000-0003-2250-3920/work/173415862ORCID: /0000-0002-8456-4473/work/177758640https://hdl.handle.net/2164/24444We would like to thank the South West Dementia Brain Bank (SWDBB) and donors for the human brain tissue provided for this study. We would like to acknowledge the University of Aberdeen core facilities of Microscopy and Histology, Iain Fraser Cytometry Centre, and Proteomics for their support with microscopy, flow cytometry and surface plasmon resonance, respectively.205060569engSubstantive connection via an eligible employment contractAlzheimer’s diseaseTauopathyTau proteinPaired helical filamentMonoclonal antibodyDiagnosticTherapyImmunotherapyRC0321 Neuroscience. Biological psychiatry. NeuropsychiatrySupplementary Informationhttps://static-content.springer.com/esm/art%3A10.1186%2Fs13195-024-01561-1/MediaObjects/13195_2024_1561_MOESM1_ESM.docxSupplementary DataDASRC0321Journal article10.1186/s13195-024-01561-1http://www.scopus.com/inward/record.url?scp=85205526769&partnerID=8YFLogxK16