Garcia-Segura, Monica EmiliDurainayagam, Brenan RLiggi, SoniaGraça, GonçaloJimenez, BeatrizDehghan, AbbasTzoulaki, IoannaKaraman, IbrahimElliott, PaulGriffin, Jules2023-04-062023-04-062022-12-26Garcia-Segura, M E, Durainayagam, B R, Liggi, S, Graça, G, Jimenez, B, Dehghan, A, Tzoulaki, I, Karaman, I, Elliott, P & Griffin, J 2022, 'Pathway-based integration of multi-omics data reveals lipidomics alterations validated in an Alzheimer´s Disease mouse model and risk loci carriers', Journal of Neurochemistry, vol. 164, no. 1, pp. 57-76. https://doi.org/10.1111/jnc.157190022-3042ORCID: /0000-0003-1336-7744/work/132961672https://hdl.handle.net/2164/20440Acknowledgements The authors would like to acknowledge Dr. Tomonori Aikawa and Professor Takahisa Kanekiyo from the Mayo Clinic, Jacksonville, Florida for providing the ABCA7 cortical mouse tissue. Funding Information Alzheimer's Research UK, Grant/Award Number: Imperial College Dementia Research Institute; Alzheimer's Society; Medical Research Council207982657engSDG 3 - Good Health and Well-beingAlzheimer's diseaseATP-binding-cassette subfamily-a member-7 gene (ABCA7)lipidomicsmetabolome-wide association study (MWAS)multi-omicspathway-based integrationRC0321 Neuroscience. Biological psychiatry. NeuropsychiatryQP PhysiologyCellular and Molecular NeuroscienceGeneral Biochemistry,Genetics and Molecular BiologyAlzheimers Research UKMedical Research Council (MRC)Supplementary DataRC0321QPJournal article10.1111/jnc.157191641