Smith, Jane RMusgrave, StanleyPayerne, EstelleNoble, MichaelSims, Erika JClark, Allan BBarton, GarryPinnock, HilarySheikh, AzizWilson, Andrew MARRISA-UK Group2018-11-162018-11-162018-08-29Smith, J R, Musgrave, S, Payerne, E, Noble, M, Sims, E J, Clark, A B, Barton, G, Pinnock, H, Sheikh, A, Wilson, A M & ARRISA-UK Group 2018, 'At-risk registers integrated into primary care to stop asthma crises in the UK (ARRISA-UK) : study protocol for a pragmatic, cluster randomised trial with nested health economic and process evaluations', Trials, vol. 19, 466. https://doi.org/10.1186/s13063-018-2816-z1745-6215PubMedCentral: PMC6116486http://hdl.handle.net/2164/11451The ARRISA-UK trial is fully funded by the NIHR Health Technology Assessment (HTA), Grant number 13/34/70. This protocol presents independent research commissioned by the NIHR. The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, the NIHR Evaluation, Trials and Studies Coordinating Centre, the HTA programme or the Department of Health. Availability of data and materials After completion of the trial the database will be retained on the servers of UEA for 15 years for on-going secondary analysis. The datasets generated and/or analysed during the current study will be available from the corresponding author on reasonable request, provided appropriate credit is attributed to the original authors and the data source.1880854engAt-risk asthmageneral practicepathway of careregisterelearninghospitalisationR MedicineNational Institute for Health Research (NIHR)13/34/70RJournal article10.1186/s13063-018-2816-z19