Turner, SteveCotton, SeonaidhWood, JessicaBell, VictoriaRaja, Edwin AmalrajScott, NeilMorgan, HeatherLawrie, LouisaEmele, DavidKennedy, CharlotteScotland, GrahamFielding, ShonaMacLennan, GraemeNorrie, JohnForrest, MarkGaillard, Erol A.de Jongste, Johan C.Pijnenburg, Mariëlle WThomas, MikePrice, David2022-11-302022-11-302022-06-06Turner, S, Cotton, S, Wood, J, Bell, V, Raja, E A, Scott, N, Morgan, H, Lawrie, L, Emele, D, Kennedy, C, Scotland, G, Fielding, S, MacLennan, G, Norrie, J, Forrest, M, Gaillard, E A, de Jongste, J C, Pijnenburg, M W, Thomas, M & Price, D 2022, 'Reducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy : a multicentre, parallel, randomised, controlled, phase 3 trial', The Lancet. Respiratory medicine, vol. 10, no. 6, pp. 584-592. https://doi.org/10.1016/S2213-2600(21)00486-02213-2600ORCID: /0000-0002-6118-8911/work/110637495ORCID: /0000-0002-1039-5646/work/110637838ORCID: /0000-0002-8067-9660/work/110638391ORCID: /0000-0003-0853-9724/work/162727494https://hdl.handle.net/2164/19642ACKNOWLEDGEMENTS We would like to thank all the children who took part in the study and their families. We are grateful to all the staff at recruitment sites that facilitated identification, recruitment and follow-up of study participants (listed below). We could not have completed the study without the ongoing support of local and primary care research networks. We are grateful for the primary care practices that acted as Participant Identification Centres and to the National Research Scotland Primary Care Network for facilitating this activity. The authors express their thanks to the staff in the primary care centres who provided primary outcome data. We are grateful to Andrea Fraser for her secretarial and data co-ordination support. We are grateful to Ruth Thomas for her help and advice in developing the grant proposal. We thank the Programming Team in CHaRT for developing and maintaining the study website and David Cooper for his statistical analysis advice. We also thank Juliette Snow and Rachael West for their help with contracting, and to Louise Cotterell, Helen Strachan, Blair Annandale and Anne Buckle for their help in managing the budget. We are very grateful for Dr Aileen Neilson for her work in establishing the Health Economic methodology. We also thank the Research Governance team (Louise King, Stacey Dawson, Lynn McKay) at the University of Aberdeen for their advice and support during the study. We acknowledge the funding provided by the National Institute of Health Research Efficacy and Mechanism Evaluation (Ref 15-18-14)91335937engAlgorithmsasthmachildClinical trialNitric OxideTherapeuticsR MedicinePulmonary and Respiratory MedicineNational Institute for Health Research (NIHR)15-18-14RJournal article10.1016/S2213-2600(21)00486-0http://www.scopus.com/inward/record.url?scp=85124876720&partnerID=8YFLogxK106