Khan, HilalGamble, DavidRudd, AmeliaDospinescu, CiprianCreaney, CalumHorgan, GrahamHolme, Andrea LWilson, HeatherNewby, David EGray, StuartKrishnadas, RajeevWilliams, ChristopherWaiter, GordonDawson, Dana2025-09-242025-10-21Khan, H, Gamble, D, Rudd, A, Dospinescu, C, Creaney, C, Horgan, G, Holme, A L, Wilson, H, Newby, D E, Gray, S, Krishnadas, R, Williams, C, Waiter, G & Dawson, D 2025, 'Takotsubo syndrome : cognitive behavioural therapy, physical training, and brain function recovery in the BREAKOUT trial', European Heart Journal, vol. 46, no. 40, pp. 4127-4129. https://doi.org/10.1093/eurheartj/ehaf4410195-668XORCID: /0000-0002-5313-9845/work/193592765ORCID: /0000-0002-1407-7274/work/193594073ORCID: /0000-0003-2815-4469/work/193594146ORCID: /0000-0002-6048-1374/work/193594322https://hdl.handle.net/2164/26073Open access via the OUP Agreement We would like to acknowledge Professor Mark Petrie, consultant cardiologist, Glasgow; Dr Stuart Watkins, consultant cardiologist, Glasgow; Dr David Corcoran, consultant cardiologist, Glasgow; Prof. Stephen Leslie, consultant cardiologist, Inverness; Dr David Carrick, consultant cardiologist, Hairmyres Hospital, Lanarkshire; Professor Chim Lang, consultant cardiologist, Dundee; and Dr Neil Anglim, consultant cardiologist, Dundee, for identifying patients recruited in this study. The authors gratefully acknowledge the BHF Cardiovascular Biomarker Laboratory, University of Edinburgh, for their assistance with this work.32742859engTakotsubo syndromeBrain functional magnetic resonance imagingExerciseCognitive behavioural therapyBehavioural modificationR Medicine (General)RC0321 Neuroscience. Biological psychiatry. NeuropsychiatrySupplementary DataDASR1RC0321Journal article10.1093/eurheartj/ehaf441