Wardlaw, Joanna M.Makin, Stephen J.Valdés Hernández, Maria C.Armitage, Paul A.Heye, Anna K.Chappell, Francesca M.Muñoz-Maniega, SusanaSakka, EleniShuler, KirstenDennis, Martin S.Thrippleton, Michael J.2020-02-182020-02-182017-06-01Wardlaw, J M, Makin, S J, Valdés Hernández, M C, Armitage, P A, Heye, A K, Chappell, F M, Muñoz-Maniega, S, Sakka, E, Shuler, K, Dennis, M S & Thrippleton, M J 2017, 'Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia : evidence from a cohort study', Alzheimer's and Dementia, vol. 13, no. 6, pp. 634-643. https://doi.org/10.1016/j.jalz.2016.09.0061552-5260RIS: urn:61418C6A91159747E9DD41B87C692411RIS: 12071ORCID: /0000-0001-8701-9043/work/76976276https://hdl.handle.net/2164/13711We thank the participants, their relatives, and carers for their time and patience in contributing to the study, the staff of NHS Lothian Stroke Services, and the Brain Research Imaging Centre Edinburgh for their assistance in recruiting and assessing the patients. Funding: Wellcome Trust (WT088134/Z/09/A), Row Fogo Charitable Trust, Scottish Funding Council Scottish Imaging Network A Platform for Scientific Excellence collaboration, Age-UK Disconnected Mind Study, NHS Lothian R+D Department, and The Brain Research Imaging Centre Edinburgh (http://www.sbirc.ed.ac.uk/). Conflict of interest: All authors report grants from Wellcome Trust, grants from Row Fogo Charitable Trust, grants from Age UK, and grants from Scottish Funding Council, during the conduct of the study. Role of the funding source: The funders had no role in the planning, execution, analysis of the study, or preparation of the manuscript or decision to submit. The authors hold the data.101664029engblood brain barriersmall vessel diseasestrokewhite matter hyperintensitiesdementiaR MedicineWellcome TrustWT088134/Z/09/AScottish Funding Councilcottish Imaging Network A Platform for Scientific Excellence collaborationSupplementary DataRJournal article10.1016/j.jalz.2016.09.006136