Eccleston, ChristopherBegley, EmmaBirkinshaw, HollieChoy, Ernest H.Crombez, GeertFisher, EmmaGooberman-Hill, RachaelGrieve, SharonGuest, AmberJordan, AbbieLilywhite, AmandaMacfarlane, GaryMcCabe, CandidaMcBeth, JohnPickering, Anthony EPincus, TamarSallis, Hannah MStone, Samanthavan der Windt, Danielle A.Vitali , DiegoWainwright, ElaineWilkinson, Colinde C Williams, Amanda CZeyen, AnicaKeogh, Edmund2023-10-032023-10-032023-10Eccleston, C, Begley, E, Birkinshaw, H, Choy, E H, Crombez, G, Fisher, E, Gooberman-Hill, R, Grieve, S, Guest, A, Jordan, A, Lilywhite, A, Macfarlane, G, McCabe, C, McBeth, J, Pickering, A E, Pincus, T, Sallis, H M, Stone, S, van der Windt, D A, Vitali , D, Wainwright, E, Wilkinson, C, de C Williams, A C, Zeyen, A & Keogh, E 2023, 'The establishment, maintenance, and adaptation of high and low impact chronic pain : a framework for biopsychosocial pain research', Pain, vol. 164, no. 10, pp. 2143-2147. https://doi.org/10.1097/j.pain.00000000000029510304-3959ORCID: /0000-0003-2322-3314/work/137686381ORCID: /0000-0002-3610-347X/work/189632600https://hdl.handle.net/2164/21820Acknowledgments This work was supported by a joint and equal investment from UKRI [grant numbers MR/W004151/1 and MR/W026872/1] and the charity Versus Arthritis [grant number 22891] through the Advanced Pain Discovery Platform (APDP) initiative. For UKRI, the initiative is led by the Medical Research Council (MRC), with support from the Biotechnology and Biological Sciences Research Council (BBSRC) and the Economic and Social Research Council (ESRC). No authors reported any conflicts of interest associated with this manuscript5170007engSDG 3 - Good Health and Well-beingR MedicineMedical Research Council (MRC)MR/W004151/1MR/W026872/1Arthritis Research UK (ARUK)22891UK Research and Innovation (UKRI)MR/W004151/1MR/W026872/1Economic and Social Research Council (ESRC)Biotechnology and Biological Sciences Research Council (BBSRC)RJournal article10.1097/j.pain.000000000000295116410