Schaefer, KatjaWagener, JeanetteAmes, Ryan MChristou, StellaMacCallum, Donna MBates, StevenGow, Neil A R2020-08-312020-08-312020-08-11Schaefer, K, Wagener, J, Ames, R M, Christou, S, MacCallum, D M, Bates, S & Gow, N A R 2020, 'Three Related Enzymes in Candida albicans Achieve Arginine- and Agmatine-Dependent Metabolism That Is Essential for Growth and Fungal Virulence', mBio, vol. 11, no. 4, e01845-20. https://doi.org/10.1128/mBio.01845-202161-2129PubMedCentral: PMC7439472ORCID: /0000-0002-7227-4348/work/79765299ORCID: /0000-0003-4833-0378/work/79765339https://hdl.handle.net/2164/15040We thank Jane Usher (University of Exeter) for constructive criticism of the manuscript. We thank Valmik K. Vyas and Gerald R. Fink from the Whitehead Institute for Biomedical Research, Cambridge, United Kingdom, for providing the Candida CRISPR plasmid (CaCas9 Solo system pV1200 vector). N.A.R.G. acknowledges support provided by Wellcome as a Senior Investigator Award (101873/Z/13/Z), Collaborative Award (200208/A/15/Z), and Strategic Award (097377/Z11/Z) and by the MRC Centre for Medical Mycology (MR/N006364/2). R.M.A. acknowledges support from an EPSRC/BBSRC Interface Innovation Fellowship (EP/S001352/1). K.S., N.A.R.G., S.B., and J.W. conceived the study. N.A.R.G. was awarded the grant that served as a resource for this study. K.S., S.C., D.M.M., and S.B. performed experiments. K.S., N.A.R.G., S.B., and R.M.A. analyzed and interpreted results. K.S., N.A.R.G., and S.B. wrote the paper, and all of us provided comments.152296926engcandidaarginaseguanidinobutyraseagmatinaseimmunitymorphogenesiscandida albicansmacrophagesCandida albicansArginaseAgmatinaseMacrophagesImmunityMorphogenesisGuanidinobutyraseCandidaDECARBOXYLASEPUTRESCINE BIOSYNTHETIC ENZYMENITRIC-OXIDEPOLYAMINE BIOSYNTHESISDEIMINASEASPERGILLUS-NIGERMECHANISMSIDENTIFICATIONGENEUREOHYDROLASEQR MicrobiologyR MedicineVirologyMicrobiologyEngineering and Physical Sciences Research Council (EPSRC)EP/S001352/1Medical Research Council (MRC)MR/N006364/2Wellcome Trust101873/Z/13/Z200208/A/15/Z097377/Z11/ZSupplementary DataQRRJournal article10.1128/mBio.01845-20http://www.scopus.com/inward/record.url?scp=85089568773&partnerID=8YFLogxK114