Paris, JasminMorgan, MarcosCampos, JoanaSpencer, Gary JShmakova, AlenaIvanova, IvaylaMapperley, ChristopherLawson, HannahWotherspoon, David ASepulveda, CatarinaVukovic, MilicaAllen, LewisSarapuu, AnnikaTavosanis, AndreaGuitart, Amelie VVillacreces, ArnaudMuch, ChristianChoe, JunhoAzar, Alivan de Lagemaat, Louie NVernimmen, DouglasNehme, AliMazurier, FredericSomervaille, Tim C PGregory, Richard IO'Carroll, DónalKranc, Kamil R2024-04-162024-04-162019-07-03Paris, J, Morgan, M, Campos, J, Spencer, G J, Shmakova, A, Ivanova, I, Mapperley, C, Lawson, H, Wotherspoon, D A, Sepulveda, C, Vukovic, M, Allen, L, Sarapuu, A, Tavosanis, A, Guitart, A V, Villacreces, A, Much, C, Choe, J, Azar, A, van de Lagemaat, L N, Vernimmen, D, Nehme, A, Mazurier, F, Somervaille, T C P, Gregory, R I, O'Carroll, D & Kranc, K R 2019, 'Targeting the RNA m 6 A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia', Cell stem cell, vol. 25, no. 1, pp. 137-148, e1-.e6. https://doi.org/10.1016/j.stem.2019.03.0211875-9777PubMedCentral: PMC6617387ORCID: /0000-0002-2947-1557/work/140426474https://hdl.handle.net/2164/23253K.R.K. is a Cancer Research UK (CRUK) Senior Cancer Research Fellow and a CRUK Programme Grant holder. This work is funded by CRUK (awards C29967/A14633 and C29967/A26787 to K.R.K.) and Wellcome (award 106144 to D.O.). K.R.K.’s laboratory is also supported by grants from The Barts Charity, Wellcome, Bloodwise, Medical Research Council, and the Kay Kendall Leukaemia Fund. D.O. is a member of the Wellcome Centre for Cell Biology supported by Wellcome core funding (award 092076). G.J.S. and T.C.P.S. are supported by CRUK (award C5759/A20971). Part of this work was carried out in the framework of the European Cost Action EPITRAN CA16120.195989263engSDG 3 - Good Health and Well-beingAnimalsCell Self RenewalHematopoiesisHematopoietic Stem CellsHumansLeukemia, Myeloid, Acute/geneticsMiceMice, Inbred C57BLMice, KnockoutNeoplastic Stem Cells/physiologyRNA, Small Interfering/geneticsRNA-Binding Proteins/geneticsTHP-1 CellsR MedicineCancer Research UKC29967/A14633C29967/A26787C5759/A20971Wellcome Trust106144092076RJournal article10.1016/j.stem.2019.03.021https://europepmc.org/articles/PMC6617387251