Latta, LorenzFigueiredo, F. C.Ashery-Padan, R.Collinson, JonDaniels, J.Ferrari, StefanoSzentmáry, N.Solá, S.Shalom-Feuerstein, R.Lako, M.Xapelli, S.Aberdam, D.Lagali, N.2022-03-222022-03-222021-10Latta, L, Figueiredo, F C, Ashery-Padan, R, Collinson, J, Daniels, J, Ferrari, S, Szentmáry, N, Solá, S, Shalom-Feuerstein, R, Lako, M, Xapelli, S, Aberdam, D & Lagali, N 2021, 'Pathophysiology of aniridia-associated keratopathy: developmental aspects and unanswered questions', The Ocular Surface, vol. 22, pp. 245-266. https://doi.org/10.1016/j.jtos.2021.09.0011542-0124https://hdl.handle.net/2164/18278This review is based upon work from the Work Group5 of the COST Action CA18116 (Aniridia: networking to address an unmet medical, scientific, and societal challenge), supported by COST (European Cooperation in Science and Technology). The European Joint Programme on Rare Diseases (EJP RD 2020) is acknowledged for its support to NL, LL, DA, MJC, NS, RAP (AAK-INSIGHT). The work of LL and NS at the Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research at Saarland University, Germany was supported by the Dr. Rolf M. Schwiete Foundation.227984709120826enganiridia-associated keratopathy (AAK)PAX6Anterior chamberdevelopmentlimbal stem cells (LSC)Aniridiaaniridia animal and cellular modelsClinical Researchresearch strategieslimbal nicheR MedicineRJournal article10.1016/j.jtos.2021.09.00122