Applied Medicine research
Permanent URI for this collectionhttps://hdl.handle.net/2164/635
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Item Identification of hip fracture patients from radiographs using Fourier analysis of the trabecular structure: a cross-sectional study(2004) Gregory, Jennifer Susan; Stewart, Alison; Undrill, Peter Edward; Reid, David M; Aspden, Richard Malcolm; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)Item Lymph node removal enhances corneal graft survival in mice at high risk of rejection(2004-03-23) Plskova, Jarka; Holan, Vladimir; Filipec, Martin; Forrester, John V; University of Aberdeen.University of Aberdeen; University of Aberdeen.Applied MedicineItem The effectiveness of metal on metal hip resurfacing : a systematic review of the available evidence published before 2002(2004-12-27) Wyness, Laura; Vale, Luke; McCormack, Kirsty; Grant, Adrian; Brazzelli, Miriam; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Applied Health SciencesItem Field-cycled PEDRI imaging of free radicals with detection at 450 mT(2005-02) Lurie, David John; Davies, Gareth Reynold; Foster, M. A.; Hutchison, James McDonald Strachan; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Does age acquired immunity confer selective protection to common serotypes of Campylobacter jejuni?(2005-08) Miller, Gordon; Dunn, Geoff M; Reid, Thomas M S; Ogden, Iain D; Strachan, Norval J C; University of Aberdeen.University of Aberdeen; University of Aberdeen.Physics; University of Aberdeen.Applied MedicineItem Selection of gonadotrophin surge attenuating factor phage antibodies by bioassay(2005-09-26) Sorsa-Leslie, Tarja Kristina; Mason, H D; Harris, William Joseph; Fowler, Paul Alfred Francois; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury(2006-01-01) Dell'Accio, Francesco; De Bari, Cosimo; El Tawil, Noha M F; Barone, Francesca; Mitsiadis, Thimios A; O'Dowd, John; Pitzalis, Costantino; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)Item Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes : the GENOMOS study(2006-02-21) Ralston, Stuart H; Uitterlinden, Andre G; Brandi, Maria Luisa; Balcells, Susana; Langdahl, Bente L; Lips, Paul; Lorenc, Roman; Obermayer-Pietsch, Barbara; Scollen, Serena; Bustamante, Mariona; Husted, Lise Bjerre; Carey, Alisoun H; Diez-Perez, Adolfo; Dunning, Alison M.; Falchetti, Alberto; Karczmarewicz, Elzbieta; Kruk, Marcin; van Leeuwen, Johannes P T M; van Meurs, Joyce B J; Mangion, Jon; McGuigan, Fiona E A; Mellibovsky, Leonardo; del Monte, Francesca; Pols, Huibert A P; Reeve, Jonathan; Reid, David M; Renner, Wilfried; Rivadeneira, Fernando; van Schoor, Natasja M; Sherlock, Rachael E; Ioannidis, John P A; GENOMOS Invest; University of Aberdeen.Applied MedicineItem Paraoxonase gene polymorphisms and haplotype analysis in a stroke population(2006-03-21) Pasdar, A; Ross-Adams, H; Cumming, A; Cheung, J; Whalley, L; St Clair, D; MacLeod, M J; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Other Applied Health SciencesItem The roles of calcium signaling and ERK1/2 phosphorylation in a Pax6(+/-) mouse model of epithelial wound-healing delay(2006-08-16) Leiper, Lucy J; Walczysko, Petr; Kucerova, Romana; Ou, Jingxing; Shanley, Lynne; Lawson, Diane; Forrester, John V; McCaig, Colin D; Zhao, Min; Collinson, J Martin; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Generation Scotland : the Scottish Family Health Study - a new resource for researching genes and heritability(2006-10-02) Smith, Blair H; Campbell, Harry; Blackwood, Douglas; Connell, John; Connor, Mike; Deary, Ian J; Dominiczak, Anna F; Fitzpatrick, Bridie; Ford, Ian; Jackson, Cathy; Haddow, Gillian; Kerr, Shona; Lindsay, Robert; McGilchrist, Mark; Morton, Robin; Murray, Graeme; Palmer, Colin N A; Pell, Jill P; Ralston, Stuart H; St Clair, David; Sullivan, Frank; Watt, Graham; Wolf, Roland; Wright, Alan; Porteous, David; Morris, Andrew D; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Applied MedicineItem The DAMASK trial protocol : a pragmatic randomised trial to evaluate whether GPs should have direct access to MRI for patients with suspected internal derangement of the knee(2006-10-13) Brealey, Stephen D; Atwell, Christine; Bryan, Stirling; Coulton, Simon; Cox, Helen; Cross, Ben; Fylan, Fiona; Garratt, Andrew; Gilbert, Fiona J; Gillan, Maureen G C; Hendry, Maggie; Hood, Kerenza; Houston, Helen; King, David; Morton, Veronica; Orchard, Jo; Robling, Michael; T Russell, Ian; Torgerson, David; Wadsworth, Valerie; Wilkinson, Clare; University of Aberdeen.Applied MedicineItem Poor glycated haemoglobin control and adverse pregnancy outcomes in type 1 and type 2 diabetes mellitus : systematic review of observational studies(2006-10-30) Inkster, Melanie E; Fahey, Tom P; Donnan, Peter T; Leese, Graham P; Mires, Gary J; Murphy, Deirdre J; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Applied Health SciencesItem Renal function, revascularization and risk(OUP, 2007) Hillis, Graham S.; Cuthbertson, Brian; Croal, Bernard L.; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Medicine; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health SciencesItem Utility of B-type natriuretic peptide in predicting medium-term mortality in patients undergoing major non-cardiac surgery(Elsevier, 2007) Cuthbertson, Brian; Amiri, Amir R.; Croal, Bernard L.; Rajagopalan, Sriram; Brittenden, Julie; Hillis, Graham S.; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health Sciences; University of Aberdeen, School of Medicine & Dentistry, Division of Applied MedicineWe assessed the ability of pre-operative B-type natriuretic peptide (BNP) levels to predict medium-term mortality in patients undergoing major noncardiac surgery. During a median 654 days follow-up 33 patients from a total cohort of 204 patients (16%) died. The optimal cut-off in this cohort, determined using a receiver operating characteristic curve, was >35pg.mL-1. This was associated with a 3.47-fold increase in the hazard of death (p=0.001) and had a sensitivity of 70% and a specificity of 68% for this outcome. These findings extend recent work demonstrating that BNP levels obtained before major noncardiac surgery can be used to predict peri-operative morbidity, and indicate that they also forecast medium-term mortality.Item Immunomodulatory properties of mesenchymal stem cells : a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005(2007-01-01) Tyndall, Alan; Walker, Ulrich A.; Cope, Andrew; Dazzi, Francesco; De Bari, Cosimo; Fibbe, Willem; Guiducci, Serena; Jones, Simon; Jorgensen, Christian; Le Blanc, Katarina; Luyten, Frank; McGonagle, Dennis; Martin, Ivan; Bocelli-Tyndall, Chiara; Pennesi, Giuseppina; Pistoia, Vito; Pitzalis, Constantino; Uccelli, Antonio; Wulffraat, Nico; Feldmann, Marc; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)Item Improving response rates using a monetary incentive for patient completion of questionnaires : an observational study(2007-02-27) Brealey, Stephen D; Atwell, Christine; Bryan, Stirling; Coulton, Simon; Cox, Helen; Cross, Ben; Fylan, Fiona; Garratt, Andrew; Gilbert, Fiona J; Gillan, Maureen G C; Hendry, Maggie; Hood, Kerenza; Houston, Helen; King, David; Morton, Veronica; Orchard, Jo; Robling, Michael; Russell, Ian T; Torgerson, David; Wadsworth, Valerie; Wilkinson, Clare; University of Aberdeen.Applied MedicineItem Is annual surveillance of all treated hypothyroid patients necessary?(2007-07-02) Viswanath, Ananth K; Avenell, Alison; Philip, Sam; Acharya, Shamsunder H; Maclennan, Graeme; Dalziel, Katherine; Pereira, Olivia; Copland, Shirley A; Bevan, John S; Abraham, Prakash; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.University of Aberdeen; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Applied Health SciencesItem Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting(Elsevier, 2007-11) Gibson, Patrick H.; Croal, Bernard L.; Small, Gary R.; Ifezulike, Ada I.; Gibson, George; Jeffrey, Robert R.; Buchan, Keith G.; El-Shafei, Hussein; Hillis, Graham S.; Cuthbertson, Brian; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Medicine; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health SciencesBackground: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior prognostic information. We hypothesized that the N/L ratio would predict the outcome of patients undergoing surgical revascularization. Methods: Baseline clinical details were obtained prospectively in 1938 patients undergoing CABG. The differential leukocyte was measured before surgery, and patients were followed-up 3.6 years later. The primary end point was all-cause mortality. Results: The preoperative N/L ratio was a powerful univariable predictor of mortality (hazard ratio [HR] 1.13 per unit, P < .001). In a backward conditional model, including all study variables, it remained a strong predictor (HR 1.09 per unit, P = .004). In a further model, including the European system for cardiac operative risk evaluation, the N/L ratio remained an independent predictor (HR 1.08 per unit, P = .008). Likewise, it was an independent predictor of cardiovascular mortality and predicted death in the subgroup of patients with a normal white blood cell count. This excess hazard was concentrated in patients with an N/L ratio in the upper quartile (>3.36). Conclusion: An elevated N/L ratio is associated with a poorer survival after CABG. This prognostic utility is independent of other recognized risk factors.Item Deletion of the dominant autoantigen in NZB mice with autoimmune hemolytic anemia : Effects on autoantibody and T-helper responses(2007-12-15) Hall, Andrew M.; Ward, Frank J.; Shen, Chia Rui; Rowe, Cliff; Bowie, Laura; Devine, Anne; Urbaniak, Stanislaw J.; Elson, Christopher J.; Barker, Robert N.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Other Applied Health Sciences