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Item Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease(2021-06-08) Bergamaschi, Laura; Mescia, Federica; Turner, Lorinda; Hanson, Aimee L.; Kotagiri, Prasanti; Dunmore, Benjamin J.; Ruffieux, Hélène; Sa, Aloka De; Huhn, Oisín; Morgan, Michael D.; Gerber, Pehuén Pereyra; Wills, Mark R.; Baker, Stephen; Calero-Nieto, Fernando J.; Doffinger, Rainer; Dougan, Gordon; Elmer, Anne; Goodfellow, Ian G.; Gupta, Ravindra K.; Hosmillo, Myra; Hunter, Kelvin; Kingston, Nathalie; Lehner, Paul J.; Matheson, Nicholas J.; Nicholson, Jeremy K.; Petrunkina, Anna M.; Richardson, Sylvia; Saunders, Caroline; Thaventhiran, James E.D.; Toonen, Erik J.M.; Weekes, Michael P.; Göttgens, Berthold; Toshner, Mark; Hess, Christoph; Bradley, John R.; Lyons, Paul A.; Smith, Kenneth G.C.; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) Covid BioResource Collaboration; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem The Rab32/BLOC-3–dependent pathway mediates host defense against different pathogens in human macrophages(2021-01-15) Baldassarre, Massimiliano; Solano Collado, Maria Virtudes; Balci, Arda; Colamarino, Rosa Angela; Dambuza, Ivy M.; Reid, Delyth M; Wilson, Heather; Brown, Gordon D; Mukhopadyay, Subhankar; Dougan, Gordon; Spano, Stefania; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Applied MedicineItem Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice(2012-10-25) Lawley, Trevor D; Clare, Simon; Walker, Alan W; Stares, Mark D; Connor, Thomas R; Raisen, Claire; Goulding, David; Rad, Roland; Schreiber, Fernanda; Brandt, Cordelia; Deakin, Laura J; Pickard, Derek J; Duncan, Sylvia H; Flint, Harry James; Clark, Taane G; Parkhill, Julian; Dougan, Gordon; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical SciencesItem High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease(2011-01-10) Walker, Alan W; Sanderson, Jeremy D; Churcher, Carol; Parkes, Gareth C; Hudspith, Barry N; Rayment, Neil; Brostoff, Jonathan; Parkhill, Julian; Dougan, Gordon; Petrovska, Liljana; University of Aberdeen.Rowett Institute