Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

Bergamaschi, L, Mescia, F, Turner, L, Hanson, A L, Kotagiri, P, Dunmore, B J, Ruffieux, H, Sa, A D, Huhn, O, Morgan, M D, Gerber, P P, Wills, M R, Baker, S, Calero-Nieto, F J, Doffinger, R, Dougan, G, Elmer, A, Goodfellow, I G, Gupta, R K, Hosmillo, M, Hunter, K, Kingston, N, Lehner, P J, Matheson, N J, Nicholson, J K, Petrunkina, A M, Richardson, S, Saunders, C, Thaventhiran, J E D, Toonen, E J M, Weekes, M P, Göttgens, B, Toshner, M, Hess, C, Bradley, J R, Lyons, P A, Smith, K G C & Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) Covid BioResource Collaboration 2021, 'Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease', Immunity, vol. 54, no. 6, pp. 1257-1275.e8. https://doi.org/10.1016/j.immuni.2021.05.010