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Item Designer cannabinoids could be the key to pain relief without adverse effects(2025-04-03) Greig, Iain; Ross, Ruth A.; University of Aberdeen.Microbiology and Immunity; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Positive allosteric modulation of the cannabinoid CB1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics(2024-10) Green, Hayley M.; Manning , Jamie J; Greig, Iain R; Finlay, David B; Ross, Ruth A.; Glass, Michelle; University of Aberdeen.Microbiology and Immunity; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity(2024-04-15) Flavin, Audrey; Azizi, Paniz; Murataeva, Natalia; Yust, Kyle; Du, Wenwen; Ross, Ruth A.; Greig, Iain; Nguyen, Thuy; Zhang, Yanan; Zhang, Yanan; Mackie, Ken; Straiker, Alex; University of Aberdeen.Microbiology and Immunity; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models(2021-01-31) Mielnik, Catharine A; Sugamori, Kim S; Finlay, David B; Thorpe, Hayley H A; Schapira, Matthieu; Sivananthan, Nirunthan; Li, Chun Kit; lam, Vincent M; Harrington, Sean; Abdelrahman, Mostafa H; Trembleau, Laurent A; Burnham, W. McIntyre; Khokhar, Jibran Y; Salahpour, Ali; Ramsey, Amy J; Glass, Michelle; Greig, Iain R.; Ross, Ruth A.; University of Aberdeen.Chemistry; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs)(2019) Tseng, Chih-Chung; Baillie, Gemma; Donvito, Giulia; Mustafa, Mohammed A.; Juola, Sophie E.; Zanato, Chiara; Massarenti, Chiara; Dall'angelo, Sergio; Harrison, William T. A.; Lichtman, Aron H.; Ross, Ruth A.; Zanda, Matteo; Greig, Iain R.; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators(2016-09-15) Greig, Iain R.; Baillie, Gemma L.; Abdelrahman, Mostafa Hamed; Trembleau, Laurent; Ross, Ruth A.; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.ChemistryItem Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice(2016-10) Khalid, Aysha B; Goodyear, Simon R; Ross, Ruth A.; Aspden, Richard M; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)Item A Cannabinoid CB 1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects(2015-12) Ignatowska-Jankowska, Bogna M.; Baillie, Gemma L.; Kinsey, Steven; Crowe, Molly; Ghosh, Sudeshna; Owens, Robert A.; Damaj, Imad M.; Poklis, Justin; Wiley, Jenny L.; Zanda, Matteo; Zanato, Chiara; Greig, Iain R.; Lichtman, Aron H.; Ross, Ruth A.; University of Aberdeen.Medical SciencesItem Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease(2015-11) Mounsey, Ross B; Mustafa, Sarah; Robinson, Lianne; Ross, Ruth A.; Riedel, Gernot; Pertwee, Roger G.; Teismann, Peter; University of Aberdeen.Medical SciencesItem Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone(2015-01-23) Khalid, Aysha B.; Goodyear, Simon R.; Ross, Ruth A.; Aspden, Richard M.; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)