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Item Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity(2024-09-06) Al-Wahaibi, Lamya H.; Abou-Zied, Hesham A.; Abdelrahman, Mostafa H.; Morcoss, Martha M.; Trembleau, Laurent; Youssif, Bahaa G.M.; Bräse, Stefan; University of Aberdeen.ChemistryItem Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors(2022-08-16) Al-Wahaibi, Lamya H.; Mostafa, Yaser A.; Abdelrahman, Mostafa H.; El-Bahrawy, Ali H.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.ChemistryItem Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways(2023-02) Al-Wahaibi, Lamya H.; Mohammed, Anber F.; Abdelrahman, Mostafa H.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.ChemistryItem Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease(2021-11-30) Al-Wahaibi, Lamya H.; Mostafa, Ahmed; Mostafa, Yaser A.; Abou-Ghadir, Ola F.; Abdelazeem, Ahmed H.; Gouda, Ahmed M.; Kutkat, Omnia; Abo Shama, Noura M.; Shehata, Mahmoud; Gomaa, Hesham A.M.; Abdelrahman, Mostafa H.; Mohamed, Fatma A.M.; Gu, Xuyuan; Ali, Mohamed A.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing SciencesItem A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif(2022-08-26) Wang, Shan; Lin, Sixing; Fang, Qing; Gyampoh, Roland; Lu, Zhou; Gao, Yingli; Clarke, David J; Wu, Kewen; Trembleau, Laurent; Yu, Yi; Kyeremeh, Kwaku; Milne, Bruce F; Tabudravu, Jioji; Deng, Hai; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing SciencesItem Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects(2021-11-01) Hendawy, O. M.; Gomaa, Hesham A.M.; Alzarea, Sami I.; Alshammari, Mutariah S.; Mohamed, Fatma A.M.; Mostafa, Yaser A.; Abdelazeem, Ahmed H.; Abdelrahman, Mostafa H.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.ChemistryItem Characterization of a class II ketol-acid reductoisomerase from Mycobacterium tuberculosis(2022) Valera, Ane; Wang, Shan; Carr, Reuben; Trembleau, Laurent; Deng, Hai; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing SciencesItem Discovery and biosynthetic investigation of a new antibacterial dehydrated non‐ribosomal tripeptide(2021-02-08) Wang, Shan; Fang, Qing; Lu, Zhou; Gao, Yingli; Trembleau, Laurent; Ebel, Rainer; Andersen, Jeanette H; Philips, Carol; Law, Samantha; Deng, Hai; University of Aberdeen.ChemistryItem Enzymatic Reconstitution and Biosynthetic Investigation of the Bacterial Carbazole Neocarazostatin A(2019-12-20) Liu, Yating; Su, Li; Fang, Qing; Tabudravu, Jioji; Yang, Xiaohui; Rickaby, Kirstie; Trembleau, Laurent; Kyeremeh, Kwaku; Deng, Zixin; Deng, Hai; Yu, Yi; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.ChemistryItem Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants(2017-10-04) Alexandru-Crivac, Cristina N.; Umeobika, Christian; Leikoski, Niina; Jokela, Jouni; Rickaby, Kirstie A.; Grilo, André M.; Sjö, Peter; Plowright, Alleyn T.; Idress, Mohannad; Siebs, Eike; Nneoyi-Egbe, Ada; Wahlsten, Matti; Sivonen, Kaarina; Jaspars, Marcel; Trembleau, Laurent; Fewer, David P; Houssen , Wael E.; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Medical Sciences