Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways

Al-Wahaibi, Lamya H.; Mohammed, Anber F.; Abdelrahman, Mostafa H.; Trembleau, Laurent; Youssif, Bahaa G.M.

Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways

Files

Al_Wahaibi_etal_M_Design_Synthesis_and_VOR.pdf (2.24 MB)

Date

2023-02

Authors

Al-Wahaibi, Lamya H.

Mohammed, Anber F.

Abdelrahman, Mostafa H.

Trembleau, Laurent

Youssif, Bahaa G.M.

Citation

Al-Wahaibi, L H, Mohammed, A F, Abdelrahman, M H, Trembleau, L & Youssif, B G M 2023, 'Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFR T790M /BRAF V600E Pathways', Molecules, vol. 28, no. 3, 1269. https://doi.org/10.3390/molecules28031269