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Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways

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dc.contributor.authorAl-Wahaibi, Lamya H.
dc.contributor.authorMohammed, Anber F.
dc.contributor.authorAbdelrahman, Mostafa H.
dc.contributor.authorTrembleau, Laurent
dc.contributor.authorYoussif, Bahaa G.M.
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.date.accessioned2023-04-05T14:22:01Z
dc.date.available2023-04-05T14:22:01Z
dc.date.issued2023-02
dc.descriptionFunding Information: This work was funded by Princess Nourah bint Abdulrahman University Researchers Supporting Project Number (PNURSP2023R3), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.en
dc.description.statusPeer revieweden
dc.format.extent2346311
dc.identifier229535997
dc.identifier69d15a7e-4b6b-441c-ba98-5cb09b99c521
dc.identifier85147964113
dc.identifier.citationAl-Wahaibi, L H, Mohammed, A F, Abdelrahman, M H, Trembleau, L & Youssif, B G M 2023, 'Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFR T790M /BRAF V600E Pathways', Molecules, vol. 28, no. 3, 1269. https://doi.org/10.3390/molecules28031269en
dc.identifier.doi10.3390/molecules28031269
dc.identifier.iss3en
dc.identifier.issn1420-3049
dc.identifier.otherORCID: /0000-0001-6376-9077/work/132961163
dc.identifier.urihttps://hdl.handle.net/2164/20416
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85147964113&partnerID=8YFLogxKen
dc.identifier.vol28en
dc.language.isoeng
dc.relation.ispartofMoleculesen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectanticanceren
dc.subjectBRAFen
dc.subjectindoleen
dc.subjectmelanomaen
dc.subjectmutant EGFRen
dc.subjectpyrroleen
dc.subjectQD Chemistryen
dc.subjectAnalytical Chemistryen
dc.subjectChemistry (miscellaneous)en
dc.subjectMolecular Medicineen
dc.subjectPharmaceutical Scienceen
dc.subjectDrug Discoveryen
dc.subjectPhysical and Theoretical Chemistryen
dc.subjectOrganic Chemistryen
dc.subjectSupplementary Informationen
dc.subjecthttps://www.mdpi.com/article/10.3390/molecules28031269/s1en
dc.subject.lccQDen
dc.titleDesign, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathwaysen
dc.typeJournal articleen

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