Applied Health Sciences (Department)
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Item The 12p13.33/RAD52 Locus and Genetic Susceptibility to Squamous Cell Cancers of Upper Aerodigestive Tract(2015-03-20) Delahaye-Sourdeix, Manon; Oliver, Javier; Timofeeva, Maria N; Gaborieau, Valérie; Johansson, Mattias; Chabrier, Amélie; Wozniak, Magdalena B; Brenner, Darren R; Vallée, Maxime P; Anantharaman, Devasena; Lagiou, Pagona; Holcátová, Ivana; Richiardi, Lorenzo; Kjaerheim, Kristina; Agudo, Antonio; Castellsagué, Xavier; MacFarlane, Tatiana; Barzan, Luigi; Canova, Cristina; Thakker, Nalin S; Conway, David I; Znaor, Ariana; Healy, Claire M; Ahrens, Wolfgang; Zaridze, David; Szeszenia-Dabrowska, Neonilia; Lissowska, Jolanta; Fabianova, Eleonora; Mates, Ioan Nicolae; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Curado, Maria Paula; Koifman, Sergio; Menezes, Ana; Wünsch-Filho, Victor; Eluf-Neto, José; Boffetta, Paolo; Garrote, Leticia Fernández; Serraino, Diego; Lener, Marcin; Jaworowska, Ewa; Lubiński, Jan; Boccia, Stefania; Rajkumar, Thangarajan; Samant, Tanuja A; Mahimkar, Manoj B; Matsuo, Keitaro; Franceschi, Silvia; Byrnes, Graham; Brennan, Paul; McKay, James D; University of Aberdeen.Dental Education; University of Aberdeen.Epidemiology GroupItem 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use(2018-10-29) Farzan, N.; Vijverberg, S. J.; Hernandez-Pacheco, N.; Bel, E. H. D.; Berce, V.; Bønnelykke, K.; Bisgaard, H.; Burchard, E. G.; Canino, G.; Celedón, J. C.; Chew, F. T.; Chiang, W. C.; Cloutier, M. M.; Forno, E.; Francis, B.; Hawcutt, D. B.; Herrera-Luis, E.; Kabesch, M.; Karimi, L.; Melén, E.; Mukhopadhyay, S.; Merid, S. K.; Palmer, C. N.; Pino-Yanes, M.; Pirmohamed, M.; Potočnik, U.; Repnik, K.; Schieck, M.; Sevelsted, A.; Sio, Y. Y.; Smyth, R. L.; Soares, P.; Söderhäll, C.; Tantisira, K. G.; Tavendale, R.; Tse, S. M.; Turner, S.; Verhamme, K. M.; Maitland-van der Zee, A.-H.; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Farr Aberdeen; University of Aberdeen.Institute of Applied Health SciencesItem The 2016 HIGh Heels: Health effects and psychosexual benefITS (HIGH HABITS) study : systematic review of reviews and additional primary studies(2017-08-01) Barnish, Max; Morgan, Heather May; Barnish, Jean; University of Aberdeen.Epidemiology Group; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Aberdeen Centre for EvaluationItem 3,7-diamino-10H-phenothiazine salts and their use : WO2007110627(2011-02-15) University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Chemistry; Wischik, Claude Michel; Rickard, Janet Elizabeth; Harrington, Charles Robert; Horsley, David; Storey, John Mervyn David; Marshall, Colin; Sinclair, James Peter; Baddeley, ThomasItem A 6-Point TACS Score Predicts In-Hospital Mortality Following Total Anterior Circulation Stroke(2016-10) Wood, Adrian D; Gollop, Nicholas D; Bettencourt-Silva, Joao H; Clark, Allan B; Metcalf, Anthony K; Bowles, Kristian M; Flather, Marcus; Potter, John F; Myint, Phyo K; University of Aberdeen.Rowett Institute; University of Aberdeen.Applied Medicine; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Institute of Applied Health SciencesItem 64-slice computed tomography angiography in the diagnosis and assessment of coronary artery disease : systematic review and meta-analysis(BMJ, 2008) Mowatt, Graham; Cook, Jonathan Alistair; Hillis, Graham Scott; Walker, Shonagh Mary; Fraser, Cynthia Mary; Jia, Xueli; Waugh, Norman Robert; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health SciencesObjective To assess whether 64-slice computed tomography (CT) angiography might replace some coronary angiography (CA) for diagnosis and assessment of coronary artery disease (CAD). Methods We searched electronic databases, conference proceedings and scanned reference lists of included studies. Eligible studies compared 64-slice CT with a reference standard of CA in adults with suspected/known CAD, reporting sensitivity and specificity or true and false positives and negatives. Data were pooled using the hierarchical summary receiver operating characteristic model. Results Forty studies were included; 28 provided sufficient data for inclusion in the meta-analyses, all using a cutoff of ≥ 50% stenosis to define significant CAD. In patient-based detection (n=1286) 64-slice CT pooled sensitivity was 99% (95% credible interval (CrI) 97 to 99%), specificity 89% (95% CrI 83 to 94%), median positive predictive value (PPV) across studies 93% (range 64 to 100%) and negative predictive value (NPV) 100% (range 86 to 100%). In segment-based detection (n=14,199) 64-slice CT pooled sensitivity was 90% (95% CrI 85 to 94%), specificity 97% (95% CrI 95 to 98%), median positive predictive value (PPV) across studies 76% (range 44 to 93%) and negative predictive value (NPV) 99% (range 95 to 100%). Conclusions 64-slice CT is highly sensitive for patient-based detection of CAD and has high NPV. An ability to rule out significant CAD means that it may have a role in the assessment of chest pain, particularly when the diagnosis remains uncertain despite clinical evaluation and simple non-invasive testing.Item AAPT Diagnostic Criteria for Fibromyalgia(2019-06) Arnold, Lesley M; Bennett, Robert M; Crofford, Leslie J; Dean, Linda E; Clauw, Daniel J; Goldenberg, Don L; Fitzcharles, Mary-Ann; Paiva, Eduardo S; Staud, Roland; Sarzi-Puttini, Piercarlo; Buskila, Dan; Macfarlane, Gary J; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Epidemiology Group; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH); University of Aberdeen.Vice Principals; University of Aberdeen.Institute of Applied Health SciencesItem ABC of obesity. Management: Part 1 - behaviour change, diet and activity(BMJ Publishing, 2006-10-07) Avenell, Alison; Sattar, Naveed; Lean, MikeItem Abdominal massage for neurogenic bowel dysfunction in people with multiple sclerosis (AMBER - Abdominal Massage for Bowel Dysfunction Effectiveness Research)- study protocol for a randomised controlled trial(2017-03-29) McClurg, Doreen; Goodman , Kirsteen; Hagen, Suzanne; Harris, Fional; Treweek, Shaun; Emmanuel, Anton; Norton, Christine; Coggrave, Maureen; Doran, Selina; Norrie, John; Donnan, Peter; Mason, Helen; Manoukian, Sarkis; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem Abdominal massage plus advice, compared with advice only, for neurogenic bowel dysfunction in MS : a RCT(2018-10) McClurg, Doreen; Harris, Fiona; Goodman, Kirsteen; Doran, Selina; Hagen, Suzanne; Treweek, Shaun; Norton, Christine; Coggrave, Maureen; Norrie, John; Rauchhaus, Petra; Donnan, Peter; Emmanuel, Anton; Manoukian, Sarkis; Mason, Helen; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Centre for Healthcare Randomised Trials (CHaRT)Item Ablative therapy for people with localised prostate cancer : a systematic review and economic evaluation(2015-07-01) Ramsay, Craig R; Adewuyi, Temitope E; Gray, Joanne; Hislop, Jenni; Shirley, Mark Df; Jayakody, Shalmini; MacLennan, Graeme; Fraser, Cynthia; MacLennan, Sara; Brazzelli, Miriam; N'Dow, James; Pickard, Robert; Robertson, Clare; Rothnie, Kieran; Rushton, Stephen P; Vale, Luke; Lam, Thomas B; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Academic Urology UnitItem “About sixty per cent I want to do it” : Health researchers’ attitudes to, and experiences of, patient and public involvement (PPI)—A qualitative interview study(2019-08) Boylan, Anne-Marie; Locock, Louise; Thomson, Richard; Staniszewska, Sophie; University of Aberdeen.Aberdeen Centre for EvaluationItem The acceptability and feasibility of weight management programmes for adults with severe obesity : A qualitative systematic review(2019) Skea, Zoë; Aceves Martins, Magaly; Robertson, Clare; de Bruin, Marijn; Avenell, Alison; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Other Applied Health SciencesItem Access to specialist care : Optimizing the geographic configuration of trauma systems(2015-11) Jansen, Jan O; Morrison, Jonathan J; Wang, Handing; He, Shan; Lawrenson, Robin; Hutchison, James D; Campbell, Marion K; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem The Accuracy of Accredited Glaucoma Optometrists in the Diagnosis and Treatment Recommendation for Glaucoma(BMJ, 2007-12) Azuara-Blanco, Augusto; Burr, Jennifer Margaret; Thomas, Ruth Elizabeth; MacLennan, Graeme Stewart; McPherson, StephenBackground/aims: To compare the diagnostic performance of accredited glaucoma optometrists (AGO) for both the diagnosis of, and decision to treat glaucoma with that of routine hospital eye care against a reference standard of expert opinion, i.e. consultant ophthalmologist with a special interest in glaucoma. Methods: A directly comparative, masked, performance study was performed in Grampian, Scotland. 165 people were invited to participate and, of those, 100 (61%) were examined. People suspected of having glaucoma underwent a full ophthalmic assessment both in a newly established, community optometry led, glaucoma management scheme and in a consultant led hospital eye service within a month. Results: The agreement between the AGO and the consultant ophthalmologist in the diagnosis of glaucoma was substantial (89%, kappa = 0.703, SE=0.083). The agreement regarding the need for treatment was also substantial (88%, kappa = 0.716, SE =0.076). The agreement between the trainee ophthalmologists and the consultant ophthalmologist in the diagnosis of glaucoma and treatment recommendation were moderate (83%, kappa = 0.541, SE = 0.098, SE = 0.98; and 81%, kappa = 0.553, SE = 0.90, respectively). The diagnostic accuracy of the optometrists in detecting glaucoma in this population was high for specificity (0.93 [95% CI 0.85 to 0.97]) but lower for sensitivity at 0.76 (95% CI 0.57 to 0.89). The performance was similar when accuracy was assessed for treatment recommendation (sensitivity, 0.73[95% CI 0.57 to 0.85]; specificity 0.96[95% CI 0.88 to 0.99]). The differences in sensitivity and specificity between AGO and junior ophthalmologist was not statistically significant.Conclusions: Community optometrists trained in glaucoma provided satisfactory decisions regarding diagnosis and initiation of treatment for glaucoma. With such additional training in glaucoma optometrists are at least as accurate as junior ophthalmologists but some cases of glaucoma missed.Item Accuracy of death certification and hospital record linkage for identification of incident stroke(2008-11-10) Sinha, Shubhada; Myint, Phyo K; Luben, Robert N; Khaw, Kay-Tee; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Institute of Applied Health SciencesItem Achieving accountability through maternal death reviews in Nigeria : a process analysis(2017-10) de Kok, Bregje; Imamura, M.; Kanguru, L.; Owolabi, O.; Okonofua, F.; Hussein, J.; University of Aberdeen.Other Applied Health SciencesItem Achieving change in primary care—causes of the evidence to practice gap : systematic reviews of reviews(2016-03-22) Lau, Rosa; Stevenson, Fiona; Ong, Bie Nio; Dziedzic, Krysia; Treweek, Shaun; Eldridge, Sandra; Everitt, Hazel; Kennedy, Anne; Qureshi, Nadeem; Rogers, Anne; Peacock, Richard; Murray, Elizabeth; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem Achieving change in primary care—effectiveness of strategies for improving implementation of complex interventions : Systematic Review of Reviews(2015-12-23) Lau, Rosa; Stevenson, Fiona; Ong, Bie Nio; Dziedzic, Krysia; Treweek, Shaun; Eldridge, Sandra; Everitt, Hazel; Kennedy, Anne; Qureshi, Nadeem; Rogers, Anne; Peacock, Richard; Murray, Elizabeth; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem Achieving Good Outcomes for Asthma Living (GOAL) : mixed methods feasibility and pilot cluster randomised controlled trial of a practical intervention for eliciting, setting and achieving goals for adults with asthma(2016-12-08) Hoskins, Gaylor; Williams, Brian; Abhyanker, Purva; Donnan, Peter; Duncan, Edward AS; Pinnock, Hilary; Van Der Pol, Marjon; Rauchhaus, Petra; Taylor, Anne; Sheikh, Aziz; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Health Economics Research Unit
