Applied Health Sciences (Department)
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Item An international study of the quality of life of adult patients treated with home parenteral nutrition(2019-08) Baxter, Janet P; Fayers, Peter M; Bozzetti, Federico; Kelly, Darlene; Joly, Francisca; Wanten, Geert; Jonkers, Cora; Cuerda, Cristina; Van Gossum, Andre; Klek, Stanislaw; Boudreault, Marie-France; Gilbert, Alain; Jobin, Manon; Staun, Michael; Gillanders, Lyn; Forbes, Alastair; O'Callaghan, Margie; Martinez Faedo, Ceferino; Brunelli, Cinzia; Mariani, Luigi; Pironi, Loris; University of Aberdeen.Other Applied Health SciencesItem The self-reported quality of life of Lithuanian children with asthma was comparable to Western populations(2018-02) Taminskiene, Vaida; Vaitkaitiene, Egle; Valiulis, Algirdas; Turner, Steve; Hadjipanayis, Adamos; Stukas, Rimantas; Valiulis, Arunas; University of Aberdeen.Farr Aberdeen; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Other Applied Health SciencesItem Overcoming barriers to the implementation of patient-reported outcomes in cancer clinical trials : The PROMOTION Registry(2014-06-06) Efficace, Fabio; Rees, Jonathan; Fayers, Peter; Pusic, Andrea; Taphoorn, Martin; Greimel, Elfriede; Reijneveld, Jaap; Whale, Katie; Blazeby, Jane; University of Aberdeen.Other Applied Health SciencesItem Validation and Reliability Testing of the EORTC QLQ-NMIBC24 Questionnaire Module to Assess Patient-reported Outcomes in Non–Muscle-invasive Bladder Cancer(2014-12) Blazeby, Jane M.; Hall, Emma; Aaronson, Neil K.; Lloyd, Lisa; Waters, Rachel; Kelly, John D.; Fayers, Peter; University of Aberdeen.Other Applied Health SciencesItem A randomised, multicentre clinical trial of specialised palliative care plus standard treatment versus standard treatment alone for cancer patients with palliative care needs : The Danish palliative care trial (DanPaCT) protocol(2013-10-24) Johnsen, Anna T.; Damkier, Anette; Vejlgaard, Tove B.; Lindschou, Jane; Sjøgren, Per; Gluud, Christian; Neergaard, Mette A.; Petersen, Morten Aa; Lundorff, Lena E.; Pedersen, Lise; Fayers, Peter; Strömgren, Annette S.; Higginson, Irene J.; Groenvold, Mogens; University of Aberdeen.Other Applied Health SciencesItem Quality of life and chronic pain four years after gastrointestinal surgery(Springer, 2006-06-02) Bruce, Julie; Krukowski, Zygmunt H.PURPOSE: Little is known about the prevalence of chronic postsurgical pain after gastrointestinal surgery. This study was designed to assess the prevalence of chronic pain and quality of life in a cohort of patients who underwent surgery for benign and malignant gastrointestinal disease. METHODS: A prospective cohort design was used to assess quality of life and morbidity at four years postoperatively in 435 patients who had upper, hepatopancreaticobiliary, small-bowel, and/or colorectal anastomotic surgery in 1999 at one regional center in Northeast Scotland. Chronic pain and quality of life were assessed by postal survey using the European Organization for Research and Treatment of Cancer Quality of Life-C30 questionnaire and McGill Pain Questionnaire. RESULTS: Of the 435 patients recruited in 1999, 135 (31 percent) had died by censor date in 2003. There was a 74 percent (n = 202) response rate from surviving patients eligible for follow-up. Prevalence of chronic pain at four years postoperatively was 18 percent (95 percent confidence interval, 13-23 percent). Pain was predominantly neuropathic in character; a subgroup reported moderate-to-severe pain. Risk factors for chronic postsurgical pain included female gender, younger age, and surgery for benign disease. Compared with those who were pain-free at follow-up, patients with chronic pain had poorer functioning, poorer global quality of life, and more severe symptoms, independent of age, gender, and cancer status. CONCLUSIONS: The prevalence of chronic pain after laparotomy for gastrointestinal malignancy and nonmalignant conditions at four years after surgery was 18 percent. These patients had significantly poorer quality of life scores independent of age, gender, and cancer status.Item A cost-utility analysis of multivitamin and multimineral supplements in men and women aged 65 years and over(Elsevier, 2007) Kilonzo, Mary Mueni; Vale, Luke David; Cook, Jonathan Alistair; Milne, Anne Catherine; Stephen, Audrey Isabella; Avenell, Alison; MAVIS Trial Group; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health SciencesBackground and Aims As people age there is a progressive dysregulation of the immune system that may lead to an increased risk of infections, which may precipitate hospital admission in people with chronic heart or respiratory diseases. Mineral and vitamin supplementation in older people could therefore influence infections in older people. However, the evidence from the available randomised controlled trials is mixed. The aim of the study was to assess the relative efficiency of multivitamin and multimineral supplementation compared with no supplementation. Methods Cost-utility analysis alongside a randomised controlled trial. Participants aged 65 years or over from six general practices in Grampian, Scotland were studied. They were randomised to one tablet daily of either a multivitamin and multimineral supplement or matching placebo. Exclusion criteria were: use of mineral, vitamin or fish oil supplements in the previous three months (one month for water soluble vitamins), vitamin B12 injection in the last three months. Results Nine hundred and ten participants were recruited (454 placebo and 456 supplementation). Use of health service resources and costs were similar between the two groups. The supplementation arm was more costly although this was not statistically significant (£15 per person, 95% CI -3.75 to 34.95). After adjusting for minimisation and baseline EQ-5D scores supplementation was associated with fewer QALYs per person (–0.018, 95% CI -0.04 to 0.002). It was highly unlikely that supplementation would be considered cost-effective. Conclusions The evidence from this study suggests that it is highly unlikely that supplementation could be considered cost-effective.
