SPIRIT 2025 explanation and elaboration : Updated guideline for protocols of randomised trials

Hróbjartsson, A, Boutron, I, Hopewell, S, Moher, D, Schulz, K F, Collins, G S, Tunn, R, Aggarwal, R, Berkwits, M, Berlin, J A, Bhandari, N, Butcher, N J, Campbell, M K, Chidebe, R C W, Elbourne, D R, Farmer, A J, Fergusson, D A, Golub, R M, Goodman, S N, Hoffmann, T C, Ioannidis, J P A, Kahan, B C, Knowles, R L, Lamb, S E, Lewis, S, Loder, E, Offringa, M, Ravaud, P, Richards, D P, Rockhold, F W, Schriger, D L, Siegfried, N L, Staniszewska, S, Taylor, R S, Thabane, L, Torgerson, D J, Vohra, S, White, I R & Chan, A W 2025, 'SPIRIT 2025 explanation and elaboration : Updated guideline for protocols of randomised trials', BMJ, vol. 389, e081660. https://doi.org/10.1136/bmj-2024-081660