Browsing by Author "Trembleau, Laurent"
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Item A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize(2017-05-18) Booth, Jonathan; Alexandru-Crivac, Christina-Nicoleta; Rickaby, Kirstie A.; Nneoyiegbe, Ada F.; Umeobika, Ugochukwu; McEwan, Andrew R.; Trembleau, Laurent; Jaspars, Marcel; Houssen, Wael E.; Shalashilin, Dmitrii V.; University of Aberdeen.Chemistry; University of Aberdeen.Medical Sciences; University of Aberdeen.Natural & Computing SciencesItem Characterization of a class II ketol-acid reductoisomerase from Mycobacterium tuberculosis(2022) Valera, Ane; Wang, Shan; Carr, Reuben; Trembleau, Laurent; Deng, Hai; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing SciencesItem Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists(2015-06) Kerr, Jamie R.; Trembleau, Laurent; Storey, John M. D.; Wardell, James L.; Harrison, William T. A.; University of Aberdeen.University of Aberdeen; University of Aberdeen.ChemistryItem Crystal structures of four indole derivatives with a phenyl substituent at the 2-position and a carbonyl group at the 3-position : the C(6) N-H⋯O chain remains the same, but the weak reinforcing inter-actions are different(2016-03-01) Kerr, Jamie R.; Trembleau, Laurent; Storey, John M. D.; Wardell, James L.; Harrison, William T. A.; University of Aberdeen.ChemistryItem Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants(2017-10-04) Alexandru-Crivac, Cristina N.; Umeobika, Christian; Leikoski, Niina; Jokela, Jouni; Rickaby, Kirstie A.; Grilo, André M.; Sjö, Peter; Plowright, Alleyn T.; Idress, Mohannad; Siebs, Eike; Nneoyi-Egbe, Ada; Wahlsten, Matti; Sivonen, Kaarina; Jaspars, Marcel; Trembleau, Laurent; Fewer, David P; Houssen , Wael E.; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity(2024-09-06) Al-Wahaibi, Lamya H.; Abou-Zied, Hesham A.; Abdelrahman, Mostafa H.; Morcoss, Martha M.; Trembleau, Laurent; Youssif, Bahaa G.M.; Bräse, Stefan; University of Aberdeen.ChemistryItem Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways(2023-02) Al-Wahaibi, Lamya H.; Mohammed, Anber F.; Abdelrahman, Mostafa H.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.ChemistryItem Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents(2023-07-22) Al-Wahaibi, Lamya H.; Mohammed, Anber F.; Abdelrahman, Mostafa H.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.ChemistryItem Design, synthesis, apoptotic, and antiproliferative effects of 5-chloro-3- (2-methoxyvinyl)-indole-2-carboxamides and pyrido[3,4-b]indol-1-ones as potent EGFRWT/EGFRT790M inhibitors(2023-05-31) Al-Wahaibi, Lamya H.; Mohammed, Anber F.; Abdel Rahman, Fatema El Zahraa S.; Abdelrahman, Mostafa H.; Gu, Xuyuan; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing SciencesItem Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators(2016-09-15) Greig, Iain R.; Baillie, Gemma L.; Abdelrahman, Mostafa Hamed; Trembleau, Laurent; Ross, Ruth A.; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.ChemistryItem Different N—H···π interactions in two indole derivatives(2016-05) Kerr, Jamie R.; Trembleau, Laurent; Storey, John M. D.; Wardell, James L.; Harrison, William T. A.; University of Aberdeen.ChemistryItem Discovery and biosynthetic investigation of a new antibacterial dehydrated non‐ribosomal tripeptide(2021-02-08) Wang, Shan; Fang, Qing; Lu, Zhou; Gao, Yingli; Trembleau, Laurent; Ebel, Rainer; Andersen, Jeanette H; Philips, Carol; Law, Samantha; Deng, Hai; University of Aberdeen.ChemistryItem Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease(2021-11-30) Al-Wahaibi, Lamya H.; Mostafa, Ahmed; Mostafa, Yaser A.; Abou-Ghadir, Ola F.; Abdelazeem, Ahmed H.; Gouda, Ahmed M.; Kutkat, Omnia; Abo Shama, Noura M.; Shehata, Mahmoud; Gomaa, Hesham A.M.; Abdelrahman, Mostafa H.; Mohamed, Fatma A.M.; Gu, Xuyuan; Ali, Mohamed A.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing SciencesItem Enzymatic Reconstitution and Biosynthetic Investigation of the Bacterial Carbazole Neocarazostatin A(2019-12-20) Liu, Yating; Su, Li; Fang, Qing; Tabudravu, Jioji; Yang, Xiaohui; Rickaby, Kirstie; Trembleau, Laurent; Kyeremeh, Kwaku; Deng, Zixin; Deng, Hai; Yu, Yi; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.ChemistryItem Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects(2021-11-01) Hendawy, O. M.; Gomaa, Hesham A.M.; Alzarea, Sami I.; Alshammari, Mutariah S.; Mohamed, Fatma A.M.; Mostafa, Yaser A.; Abdelazeem, Ahmed H.; Abdelrahman, Mostafa H.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.ChemistryItem Physicochemical Tools : Toward a Detailed Understanding of the Architecture of Targeted Radiotherapy Nanoparticles(2018) Cabello, Gema; Nwoko, Kenneth C.; Mingarelli, Marco; McLaughlin, Abbie C.; Trembleau, Laurent; Feldmann, Joerg; Cuesta Ciscar, Angel; Smith, Tim A. D.; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Energy; University of Aberdeen.Centre for Energy Transition; University of Aberdeen.Applied MedicineItem A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif(2022-08-26) Wang, Shan; Lin, Sixing; Fang, Qing; Gyampoh, Roland; Lu, Zhou; Gao, Yingli; Clarke, David J; Wu, Kewen; Trembleau, Laurent; Yu, Yi; Kyeremeh, Kwaku; Milne, Bruce F; Tabudravu, Jioji; Deng, Hai; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing SciencesItem Structure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptide(2020-02-19) Idress, Mohannad; Milne, Bruce F.; Thompson, Gary S.; Trembleau, Laurent; Jaspars, Marcel; Houssen, Wael E; University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors(2022-08-16) Al-Wahaibi, Lamya H.; Mostafa, Yaser A.; Abdelrahman, Mostafa H.; El-Bahrawy, Ali H.; Trembleau, Laurent; Youssif, Bahaa G.M.; University of Aberdeen.ChemistryItem A Unique Tryptophan C‐Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway(2016-03-07) Parajuli, Anirudra; Kwak, Daniel H.; Dalponte, Luca; Leikoski, Niina; Galica, Tomas; Umeobika, Ugochukwu; Trembleau, Laurent; Bent, Andrew; Sivonen, Kaarina; Wahlsten, Matti; Wang, Hao; Rizzi, Ermano; De Bellis, Gianluca; Naismith, James; Jaspars, Marcel; Liu, Xinyu; Houssen, Wael; Fewer, David Peter; University of Aberdeen.Chemistry; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.Medical Sciences